6-氨基己酸

6-Aminocaproic acid (订货以英文为准)

编号:A103971
CAS号:60-32-2
分子式:C6H13NO2
分子量:131.17
货号 品牌 包装 目录价 您的价格 库存 数量 购买
A103971-500g 阿拉丁 500g ¥949.00
A103971-100g 阿拉丁 100g ¥279.00
A103971-2.5kg 阿拉丁 2.5kg ¥3999.00
产品名称 6-Aminocaproic acid
中文名称 6-氨基己酸
CAS号 60-32-2
分子式(M.F.) C6H13NO2
分子量(M.W.) 131.17
熔点204-209°C
敏感性对空气敏感
溶解性Soluble in water (50 mg/ml), ethanol (≥1 mg/ml), methanol (sparingly soluble), ether, and DMSO (≥6 mg/ml).
存贮条件储存温度2-8℃ 充氩保存
密度1.0420
应用EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature.
产品介绍ε-Amino-n-caproic Acid (EACA) is an antifibrinolytic agent shown to enhance the activation of urinary-type and tissue-type plasminogen, while inhibiting plasminogen activation induced by streptokinase through a kringle-dependent mechanism. Believed to act as a lysine analog that competitively inhibits basic carboxypeptidases, and promotes the rapid dissociation of plasmin by inhibiting activation of plasminogen by streptokinase. Incorporation of EACA into short polypeptide fragments with hydrophobic amino acids yielded cytotoxic compounds against MCF-7 breast cells and fibroblast cells. These factors make EACA a potentially useful compound for research in areas such as: oncology, immunology, and in the general elucidation of biochemical pathways.
生化机理EACA被报道能够抑制糜蛋白酶、因子VIIA、赖氨酸碳氧基肽酶、纤溶酶,纤溶酶原激活物。赖氨酸类似物。促进纤溶酶快速解离,从而抑制纤溶酶原?的活化以及后续的纤维蛋白溶解。据报告,EACA 可抑制纤溶酶原结合至活化的血小板。早期报告表明,EACA 可抑制补体系统第一组分的活化。结合并灭活羧肽酶 B。
别名6-氨基己酸 ;氨基己酸,氨己酸,抗血纤溶酸,ε氨基已酸,6-氨基正己酸; EACA;ε-Aminocaproic acid6-Aminohexanoic acidEACAHemocaprol
安全声明(欧洲)S24/25
搜索质检报告(COA)
搜索MSDS
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