| 旋光率 | +46 to +52°, c = 1.0 in DMSO |
| 溶解性 | DMSO |
| 存贮条件 | 储存温度2-8℃ |
| 应用 | A gastroprokinetic, peripheral μ-opioid receptor antagonist. |
| 产品介绍 | Alvimopan is a gastroprokinetic, peripheral-μ-opioid receptor antagonist. |
| 生化机理 | Alvimopan(ADL 8-2698; Entereg; LY 246736) is a selective and competitive antagonist at mu-opioid receptors, found in myenteric and submucosal neurons and the immune cells of the lamina propria in the human gut. Upon administration, Alvimopan(ADL 8-2698; Entereg; LY 246736) binds to mu-opioid receptors in the gut, thereby reversing opiod-related disturbances in gut motility. Alvimopan is approximately three to nine times more potent than naloxone.A synthetic trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. |
| 别名 | 爱维莫潘; 2-([(2S)-2-([(3R,4R)-4-(3-羟基苯基)-3,4-二甲基哌啶-1-基]甲基)-3-苯基丙酰]氨基)乙酸;ADL 8-2698; Entereg; LY 246736;2-([(2S)-2-([(3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]methyl)-3-phenylpropanoyl]amino)acetic acid |
阿尔维莫潘
Alvimopan （订货以英文为准）
编号：A124975
CAS号：156053-89-3
分子式：C25H32N2O4
分子量：424.53
| 产品名称 | Alvimopan |
| 中文名称 | 阿尔维莫潘 |
| CAS号 | 156053-89-3 |
| 分子式（M.F.） | C25H32N2O4 |
| 分子量（M.W.） | 424.53 |
| 储存条件 | 2-8°C储存 |
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