1,4-二氢-6-甲基喹喔啉-2,3-二酮

1,4-Dihydro-6-methylquinoxaline-2,3-dione (订货以英文为准)

编号:D155127
CAS号:6309-61-1
分子式:C9H8N2O2
分子量:176.18
货号 品牌 包装 目录价 您的价格 库存 数量 购买
D155127-5g 阿拉丁 5g ¥129.90
D155127-25g 阿拉丁 25g ¥399.90
产品名称 1,4-Dihydro-6-methylquinoxaline-2,3-dione
中文名称 1,4-二氢-6-甲基喹喔啉-2,3-二酮
CAS号 6309-61-1
MDL编码 D155127
分子式(M.F.) C9H8N2O2
分子量(M.W.) 176.18
别名;['6-Methyl-1,4-dihydroquinoxaline-2,3-dione', '6-Methylquinoxaline-2,3-diol']

技术规格

Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Applications: WB, IF
Name of antibody: H2AFX (Phospho-Ser139)
Immunogen: Synthetic peptide of human H2AFX (Phospho-Ser139)
Full name: H2A histone family, member X (Phospho-Ser139)
Synonyms: H2AX; H2A.X; H2A/X
SwissProt: P16104
WB Predicted band size: 15 kDa
WB Positive control: HT29 cells treated with UV
WB Recommended dilution: 500-1000
IF Positive control: Hela cells
IF Recommended dilution 100-200
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