| 溶解性 | DMSO 0.002 mg/mL Water 0.002 mg/mL Ethanol 0.01 mg/mL |
| 存贮条件 | 储存温度2-8℃ |
| 备注 | BAY 80-6946 is a potent and highly selective reversible PI3K inhibitor for PI3Kα/β with IC50 of 0.469 nM/3.72 nM. Phase 1. |
| 生化机理 | BAY 80-6946 is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BAY 80-6946 inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents. |
| 别名 | 5-Pyrimidinecarboxamide, 2-amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-;5-Pyrimidinecarboxamide, 2-amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]- |
库潘尼西
BAY 80-6946 (Copanlisib) （订货以英文为准）
编号：B129540
CAS号：1032568-63-0
分子式：C23H28N8O4
分子量：480.52
| 产品名称 | BAY 80-6946 (Copanlisib) |
| 中文名称 | 库潘尼西 |
| CAS号 | 1032568-63-0 |
| 分子式（M.F.） | C23H28N8O4 |
| 分子量（M.W.） | 480.52 |
| 储存条件 | -20°C储存 |
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