6-硫鸟嘌呤

6-Thioguanine (订货以英文为准)

编号:T106639
CAS号:154-42-7
分子式:C5H5N5S
分子量:167.19
货号 品牌 包装 目录价 您的价格 库存 数量 购买
T106639-1g 阿拉丁 1g ¥266.90
T106639-5g 阿拉丁 5g ¥777.90
T106639-25g 阿拉丁 25g ¥3411.90
产品名称 6-Thioguanine
中文名称 6-硫鸟嘌呤
CAS号 154-42-7
分子式(M.F.) C5H5N5S
分子量(M.W.) 167.19
熔点360°C
应用抗肿瘤。
产品介绍6-Thioguanine is a chemotherapy drug that demonstrates immunosuppressive, anti-neoplastic, and anti-cancer activities. This chemical is often used to treat leukemia and inflammatory diseases. Chemical produces dose-dependent inhibition of stimulated expression of TRAIL protein.
生化机理Antimetabolite used in the treatment of leukemias. Competes with hypoxanthine and guanine for the enzyme hypoxanthine-guanine phosphoribosyltransferase, which catalzyes a critical step in the generation of purine nucleotides.Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia.
别名2-氨基-6-巯基嘌呤; 6-硫代鸟嘌呤; 2-氨基-6-巯嘌呤;2-Amino-6-mercaptopurine; 2-Amino-6-purinethiol; 6-Mercaptoguanine
Merck Index4391
标识符号https://www.aladdin-e.com/images/ghs/ghs07.jpg
信号词Warning
危害声明H302
个人防护设备Eyeshields,Faceshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
RTECSNR2392000
WGK德国3
安全声明(欧洲)S24/25;
搜索质检报告(COA)
搜索MSDS
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