| 存贮条件 | 储存温度-20°C |
| 应用 | A HIV-1 reverse transcriptase (HIV-1 RT) inhibitor |
| 产品介绍 | Emtricitabine 是一种核苷逆转录酶抑制剂，IC50为27.7 μM |
| 备注 | Emtricitabine (Emtriva) is a nucleoside reverse transcriptase inhibitor with an IC50 of 27.7 μM. |
| 生化机理 | Emtricitabine is a nucleoside analogue which inhibits the reverse nucleoside transcriptase enzyme. Structurally this antiviral agent is similar to Lamivudine. This agent is effective at targeting HIV and HBV viruses since these viruses replicate in a reverse transcriptase manner. Studies indicate that the structure of Emtricitabine, specifically the unnatural β-L structural configuration produce greater antiviral effects in vitro on HIV and HBV than other antiviral agents. To activate Emtricitabine it needs to undergo multistep intracellular phosphorylation by various cellular kinases. These studies suggest that Emtricitabine competitively inhibits HIV-1 reverse transcriptase (HIV-1 RT) and can cause termination of DNA chain elongation in the virus via incorporation into the viral genome. |
| 别名 | 恩曲他滨;5-氟-1-(2R,5S)-[2-羟甲基-1,3-氧硫环-5-酰]胞嘧啶;依曲西他滨;盐酸恩曲他滨;恩曲他滨 EMTRIVA;恩曲他滨 EMTRICITABINE;Emtriva;Coviracil;BW1592;BW-1592;BW 1592;Atripla; |
恩曲他滨
Emtricitabine （订货以英文为准）
编号：E125328
CAS号：143491-57-0
分子式：C8H10N3O3FS
分子量：247.25
| 产品名称 | Emtricitabine |
| 中文名称 | 恩曲他滨 |
| CAS号 | 143491-57-0 |
| 分子式（M.F.） | C8H10N3O3FS |
| 分子量（M.W.） | 247.25 |
| 储存条件 | -20°C储存 |
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