| 溶解性 | 25°C: DMSO 2mg/mL |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | BAM7是一种直接的，选择性的促凋亡Bax激动剂，EC50为3.3 μM |
| 备注 | BAM 7 is a direct and selective activator of proapoptotic Bax with EC50 of 3.3 μM. |
| 生化机理 | BAM7 is a selective activator of BAX, a proapoptotic member of the BCL-2 protein family. BAM7 binds directly to the BAX trigger site, a distinct BH3 binding site that regulates BAX activation, inducing BAX oligomerization, which enables the release of apoptogenic factors that result in cell death. BAM7 is selective for this previously unknown BH3-binding groove on the N-terminal face of BAX |
| 别名 | 3-甲基-1-(4-苯基-2-噻唑基)-1H-吡唑-4,5-二酮 4-[2-(2-乙氧基苯基)腙];BAM 7;BAM-7；4-(2-(2-Ethoxyphenyl)hydrazono)-3-methyl-1-(4-phenylthiazol-2-yl)-1H-pyrazol-5(4H)-one；BAX activator molecule 7 |
BAM7,Bax活化剂
BAM7 （订货以英文为准）
编号：B125119
CAS号：331244-89-4
分子式：C21H19N5O2S
分子量：405.47
| 产品名称 | BAM7 |
| 中文名称 | BAM7,Bax活化剂 |
| CAS号 | 331244-89-4 |
| 分子式（M.F.） | C21H19N5O2S |
| 分子量（M.W.） | 405.47 |
| 储存条件 | -20°C储存 |
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