熔点 | 253° C |
溶解性 | Soluble in water, DMSO, ethanol, methanol, and chloroform. |
存贮条件 | 储存温度-20°C |
应用 | An antiandrogen that inhibits 5α-Reductase 2 |
产品介绍 | Finasteride是口服活性的睾酮5α-还原酶抑制剂,Ki为10 nM。 |
生化机理 | Finasteride is a synthetic 4-azasteroid antiandrogen compound. This specifically inhibits 5α-Reductase 2, an intracellular enzyme that converts the androgen testosterone into 5α dihydrotestosterone (DHT). Finasteride inhibits 5α-reductase activity in epithelium for Ki of 10nM, significantly lower than in stroma (Ki = 33nM). Finasteride is an inhibitor of 5α-Reductase 1. |
别名 | 非那甾胺; 非那雄胺;N-叔丁基-3-氧代-4-氮杂-5α-雄甾-1-烯-17β-甲酰胺; N-(2-甲基-2-丙基)-3-氧代-4-氮杂-5α-雄甾-1-烯-17β-甲酰胺;MK-906;N-tert-Butyl-3-oxo-4-aza-5α-androst-1-en-17β-carboxamide |
非那甾胺
Finasteride (订货以英文为准)
编号:F156753
CAS号:98319-26-7
分子式:C23H36N2O2
分子量:372.54
产品名称 | Finasteride |
中文名称 | 非那甾胺 |
CAS号 | 98319-26-7 |
分子式(M.F.) | C23H36N2O2 |
分子量(M.W.) | 372.54 |
储存条件 | -20°C储存 |
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