| 熔点 | 297~299℃ |
| 溶解性 | Soluble in DMSO (4 mg/ml ,warming to 60 °C for 15 minutes) DMF (1.5 mg/ml) at 37 °C, and water (slightly soluble) at 37 °C. Insoluble in ethanol. |
| 存贮条件 | 储存温度-20°C |
| 应用 | A TLR7 activator and angiogenesis inhibitor. |
| 产品介绍 | |
| 生化机理 | Imiquimod is a derivative of imidazoquinolinamine that inhibits angiogenesis and is an immune response modifier. Studies have reported that Imiquimod has the ability to downregulate metastasis and induce alpha-interferon (IFN-α). Additionally, Imiquimod is a TLR7 (toll-like receptor 7) agonist which induces plasmacytoid dendritic cell (pDC) maturation. Imiquimod acts on dendritic cells expressing TLR7, and induces an immune response. Nuclear factor-B helps mediate the activity of Imiquimod, and is involved in increasing chemokine and cytokine levels. The antiangiogenic property of Imiquimod has been shown to be mediated by IL-18. Research shows that Imiquimod can induce apoptosis in cancer cells. Also suggested to be an activator of caspase-3 and NFκB. |
| 别名 | 咪喹莫特; 1-异丁基-1H-咪唑[4.5-C]喹啉-4-胺基;1-(2-甲基丙基)-4-氨基-1H-咪唑并[4,5-c]喹啉;Aldara; R 837; Zyclara;1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine;4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline;1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine |
咪喹莫特
Imiquimod （订货以英文为准）
编号：I129798
CAS号：99011-02-6
分子式：C14H16N4
分子量：240.31
| 产品名称 | Imiquimod |
| 中文名称 | 咪喹莫特 |
| CAS号 | 99011-02-6 |
| 分子式（M.F.） | C14H16N4 |
| 分子量（M.W.） | 240.31 |
| 储存条件 | -20°C储存 |
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