敏感性 | 对热敏感 |
溶解性 | Soluble in water (25 mg/mL), DMSO (>10 mg/mL), and ethanol. |
存贮条件 | 储存温度-20°C |
应用 | An H1-receptor antagonist with antiallergic effects and disrupts TNF alpha activity. |
产品介绍 | Azelastine HCl是有效的,第二代选择性组胺拮抗剂。 |
备注 | Azelastine hydrochloride (Astelin) is a potent, second-generation, selective, histamine antagonist. |
生化机理 | Azelastine HCl is an Histamine H1 Receptor (H1-receptor) antagonist, with antiallergic effects related to histamine antagonism, and further antiallergic and antiinflammatory effects unrelated to H1-receptor binding. Azelastine is shown to block secretion of IL-6, IL-8, and TNF alpha from mast cells by inhibiting NF-κB activation. Azelastine HCl is an activator of NF κ B. |
别名 | 4-(4-氯苄基)-2-(1-甲基氮杂卓-4-基)-1-酞嗪酮盐酸盐;氮?斯汀盐酸盐;盐酸氮?斯汀;Astelin;Optivar;4-(4-Chlorobenzyl)-2-(1-methylazepan-4-yl)-1-phthalazinone Hydrochloride;Allergodil; Rhinolast; Optilas |
氮卓斯汀盐酸盐
Azelastine HCl (订货以英文为准)
编号:A129214
CAS号:79307-93-0
分子式:C22H24CLN3O.HCL
分子量:418.36
产品名称 | Azelastine HCl |
中文名称 | 氮卓斯汀盐酸盐 |
CAS号 | 79307-93-0 |
分子式(M.F.) | C22H24CLN3O.HCL |
分子量(M.W.) | 418.36 |
储存条件 | -20°C储存 |
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