| 溶解性 | DMSO ≥78mg/mL Water <1.2mg/mL Ethanol <1.2mg/mL |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | Elesclomol (STA-4783)是新型氧化应激诱导剂，能促肿瘤细胞凋亡。 |
| 备注 | Elesclomol (STA-4783) is a novel potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells. |
| 生化机理 | Elesclomol significantly induces the expression of heat shock stress response genes and metallothionein genes, a signature transcription profile indicative of oxidative stress in Hs294T cells。Elesclomol significantly inhibits the cell viability of SK-MEL-5, MCF-7, and HL-60 with IC50 of 110 nM, 24 nM and 9 nM, respectively.Elesclomol induces copper-dependent ROS generation and cytoxicity in yeast. |
| 别名 | STA-4783；伊利司莫; 丙二酸-1,3-二(2-甲基-2-(苯基硫酮甲基)酰肼);;STA-4783;STA4783;STA 4783； 1,3-bis(2-methyl-2-(phenylthioxomethyl)hydrazide)propanedioic acid |
伊利司莫(STA-4783)
Elesclomol (STA-4783) （订货以英文为准）
编号：E126032
CAS号：488832-69-5
分子式：C19H20N4O2S2
分子量：400.52
| 产品名称 | Elesclomol (STA-4783) |
| 中文名称 | 伊利司莫(STA-4783) |
| CAS号 | 488832-69-5 |
| 分子式（M.F.） | C19H20N4O2S2 |
| 分子量（M.W.） | 400.52 |
| 储存条件 | -20°C储存 |
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