柠檬酸伊沙佐米(MLN9708)

MLN9708 (订货以英文为准)

编号:M129243
CAS号:1201902-80-8
分子式:C20H23BCL2N2O9
分子量:517.12
货号 品牌 包装 目录价 您的价格 库存 数量 购买
M129243-10mg 阿拉丁 10mg ¥226.90
M129243-5mg 阿拉丁 5mg ¥147.90
M129243-1g 阿拉丁 1g ¥3246.90
M129243-500mg 阿拉丁 500mg ¥2029.90
M129243-100mg 阿拉丁 100mg ¥561.90
M129243-50mg 阿拉丁 50mg ¥385.90
产品名称 MLN9708
中文名称 柠檬酸伊沙佐米(MLN9708)
CAS号 1201902-80-8
分子式(M.F.) C20H23BCL2N2O9
分子量(M.W.) 517.12
储存条件 -20°C储存
溶解性DMSO 103 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
存贮条件储存温度-20°C
产品介绍MLN9708 immediately hydrolyzed to MLN2238, the biologically active form, on exposure to aqueous solutions or plasma. MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM.
备注MLN9708 immediately hydrolyzed to MLN2238, the biologically active form, on exposure to aqueous solutions or plasma. MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM
生化机理MLN9708 immediately hydrolyzed to MLN2238, which is an N-capped dipeptidyl leucine boronic acid and preferentially bound to and inhibited the 20S proteasome with an IC50 value of 3.4 nM (Ki = 0.93 nM).
别名4-羧基-2-[(1R)-1-[[2-[(2,5-二氯苯甲酰基)氨基]乙酰基]氨基]-3-甲基丁基]-6-氧代-1,3,2-二氧硼杂环己-4-乙酸; MLN 9708; MLN-9708;Ixazomib; MLN 9708; MLN-9708;4-Carboxy-2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-acetic acid
搜索质检报告(COA)
搜索MSDS
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